BDBM25432 6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluoromethyl)pyridine-3-carbonitrile::CHEMBL248690::aminopyridylnitrile, 13

SMILES C[C@@H](N(C)c1cc(c(cn1)C#N)C(F)(F)F)c1ccccc1

InChI Key InChIKey=WSOLZTILLRNJPH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25432   

TargetAndrogen receptor(Human)
Pfizer

LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)
Affinity DataIC50: 20nMpH: 7.4 T: 2°CAssay Description:The competitive radio-ligand binding analysis was performed on human AR extracts from transfected Sf9 cells in the presence or absence of differing c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2008
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)
Affinity DataIC50: 45nMAssay Description:Antagonist activity at human androgen receptor expressed in MDA-MB-453 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

LigandPNGBDBM25432(6-{methyl[(1R)-1-phenylethyl]amino}-4-(trifluorome...)
Affinity DataIC50: 20nMAssay Description:Displacement of [3H]dihydrotestosterone from human androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed