BDBM255486 US9499493, R935138

SMILES Oc1cccc(Nc2ncc(F)c(Nc3ccc(OCc4nc(no4)-c4ccccc4)cc3)n2)c1

InChI Key InChIKey=MZMAHCPFHFTHPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 255486   

TargetTyrosine-protein kinase SYK(Human)
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM255486(US9499493, R935138)
Affinity DataIC50: 229nMpH: 7.4 T: 2°CAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/23/2017
Entry Details
Go to US Patent