BDBM256348 US9487490, 1L

SMILES Cc1cccc(Cl)c1C(=O)n1nc(C2=CCC(CC2)C(O)=O)c2ncccc12

InChI Key InChIKey=WGVKQEUIMVZKMX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 256348   

TargetIsoform 2 of Nuclear receptor ROR-gamma (RORgT)(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM256348(US9487490, 1L)
Affinity DataIC50: 123nMpH: 7.0 T: 2°CAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/30/2017
Entry Details
US Patent