BDBM25644 (1Z)-5-[1-methyl-3-(1,3-oxazol-5-yl)-1H-pyrazol-4-yl]-2,3-dihydro-1H-indene-1-hydroxylamine::pyrazole-based inhibitor, 26

SMILES Cn1cc(c(n1)-c1cnco1)-c1ccc2C(CCc2c1)N=O

InChI Key InChIKey=ZLUOUODRGRXXJG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25644   

TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

LigandPNGBDBM25644((1Z)-5-[1-methyl-3-(1,3-oxazol-5-yl)-1H-pyrazol-4-...)
Affinity DataIC50: 4.10nMpH: 7.2 T: 2°CAssay Description:Activity of human recombinant B-Raf protein was assessed in vitro by assay of the incorporation of radiolabeled phosphate to recombinant MAP kinase (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/23/2008
Entry Details Article
PubMed