BDBM258592 US9493490, 6-(4-(Aminomethyl)-2-chlorophenoxy)-7-ethylbenzo[c][1,2]oxaborol-1(3H)-ol::US9493490, A::US9493490, Example 1

SMILES CCc1c2B(O)OCc2ccc1Oc1ccc(CN)cc1Cl

InChI Key InChIKey=COMXZDRMWBVFJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 258592   

TargetGlutathione S-transferase P/Rho-associated protein kinase 2 [5-554](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258592(US9493490, Example 1 | US9493490, 6-(4-(Aminomethy...)
Affinity DataIC50: 250nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent

TargetGlutathione S-transferase P/Rho-associated protein kinase 1 [1-535](Human)
Anacor Pharmaceuticals

US Patent
LigandPNGBDBM258592(US9493490, Example 1 | US9493490, 6-(4-(Aminomethy...)
Affinity DataIC50: 290nMT: 2°CAssay Description:Phosphorylation of activity of ROCK1 and ROCK2 and those of other kinases, AKT1, GRK2, PKA, PKCa and RSK1 were performed by Reaction Biology (Malvern...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
US Patent