BDBM25910 3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide::BMC173212 Compound 2f::indole sulfonamide, 8f

SMILES NNC(=O)c1[nH]c2ccc(cc2c1-c1ccc(F)cc1)S(N)(=O)=O

InChI Key InChIKey=RKJALVWPURNLMT-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 25910   

TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  6nM ΔG°:  -11.2kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  7.80nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  15.5nM ΔG°:  -10.6kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  49nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  54nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  58nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  61nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  65nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  108nM ΔG°:  -9.50kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  576nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  705nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  740nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  3.65E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  3.98E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Istanbul University

LigandPNGBDBM25910(BMC173212 Compound 2f | 3-(4-fluorophenyl)-2-(hydr...)
Affinity DataKi:  7.50E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed