BDBM25912 3-(3-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide::BMC173212 Compound 2h::indole sulfonamide, 8h

SMILES NNC(=O)c1[nH]c2ccc(cc2c1-c1cccc(Cl)c1)S(N)(=O)=O

InChI Key InChIKey=RCWSBQCWRNEOFW-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 25912   

TargetCarbonic anhydrase 14(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  8.5nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  9.20nM ΔG°:  -11.0kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetAlpha-carbonic anhydrase domain-containing protein(Caenorhabditis elegans)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  10.1nM ΔG°:  -10.9kcal/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2009
Entry Details Article
PubMed
TargetCarbonic anhydrase(Yeast)
Istanbul University

Curated by ChEMBL
LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  52nMAssay Description:inhibition of Candida albicans recombinant Nce103 after 15 mins by stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetCarbonic anhydrase 15 [19-324](Mouse)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  53nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  70nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  72nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  73nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  311nM ΔG°:  -8.87kcal/molepH: 7.4 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  743nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Mouse)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  816nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  844nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  5.57E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  6.14E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
Istanbul University

LigandPNGBDBM25912(BMC173212 Compound 2h | 3-(3-chlorophenyl)-2-(hydr...)
Affinity DataKi:  6.20E+6nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2008
Entry Details Article
PubMed