BDBM259374 US9505745, 51::US9790212, Example 51

SMILES CCN([C@H]1CC[C@@H](CC1)N(C)C)c1sc(C#N)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C

InChI Key InChIKey=XXQHACAXRPGDPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 259374   

LigandPNGBDBM259374(US9505745, 51 | US9790212, Example 51)
Affinity DataIC50: 25nMAssay Description:Protocol 2: Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Hu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2017
Entry Details
Go to US Patent

LigandPNGBDBM259374(US9505745, 51 | US9790212, Example 51)
Affinity DataIC50: 25nMAssay Description:Compounds contained herein were evaluated for their ability to inhibit the methyltransferase activity of EZH2 within the PRC2 complex. Human PRC2 com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
Go to US Patent