BDBM26108 (2R)-2-(formamidoformic acid)-4-phenylbutanoic acid::N-Oxalyl-D-homophenylalanine, 1c

SMILES OC(=O)[C@@H](CCc1ccccc1)NC(=O)C(O)=O

InChI Key InChIKey=DJQUHFFTFICUIW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 26108   

TargetLysine-specific demethylase 4E(Human)
University of Oxford

LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:A coupled-assay for JMJD2E activity employing formaldehyde dehydrogenase (FDH) from Pseudomonas putida was developed. Formaldehyde release by demethy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human PHD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha inhibitor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM26108((2R)-2-(formamidoformic acid)-4-phenylbutanoic aci...)
Affinity DataKi:  8.30E+4nMAssay Description:Inhibition of asparaginyl hydroxylase factor-inhibiting-HIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed