BDBM26124 CHEMBL336239::Phenylboronic Acid, 3::[3-(trifluoromethyl)phenyl]boranediol

SMILES OB(O)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=WOAORAPRPVIATR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26124   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Oxford

LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataIC50: 80nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Oxford

LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataIC50: 3.80E+4nMAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2008
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for its specificity against alpha-chymotrypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataIC50: 5.00E+3nMAssay Description:Compound was tested for its specificity against AmpC beta-lactamaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrypsin-2(Human)
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for its specificity against beta-trypsinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBeta-lactamase(Escherichia coli (strain K12))
Northwestern University Medical School

Curated by ChEMBL
LigandPNGBDBM26124([3-(trifluoromethyl)phenyl]boranediol | CHEMBL3362...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibitory activity against Escherichia coli AmpC beta-lactamase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed