BDBM261709 5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5'-methoxy-3 -methyl-1 ,2 ,3 ,6 -tetrahydro-[3,3':6',4 -terpyridin]-6-amine::US9708295, 51

SMILES COc1cc(cnc1C1=CCNCC1C)-c1cnc(N)c(O[C@H](C)c2c(Cl)ccc(F)c2Cl)c1

InChI Key InChIKey=NCXWKAVBQVPGGO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 261709   

TargetALK tyrosine kinase receptor(Human)
Chia Tai Tianqing Pharmaceutical Group

US Patent
LigandPNGBDBM261709(5-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5'-m...)
Affinity DataIC50: 46.8nMAssay Description:The following method was used to determine ALK kinase inhibitory activity of the compounds of the present invention. The inhibitory activity is indic...More data for this Ligand-Target Pair
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Date in BDB:
10/30/2018
Entry Details
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