BDBM261844 2-(9-Ethyl-9H-carbazol-3-y1)-1-methyl-1 H-benzimidazole-5-carboxylic acid::US9708311, 94

SMILES CCn1c2ccccc2c2cc(ccc12)-c1nc2cc(ccc2n1C)C(O)=O

InChI Key InChIKey=VTAXFHATHOHPMA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 261844   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM261844(2-(9-Ethyl-9H-carbazol-3-y1)-1-methyl-1 H-benzimid...)
Affinity DataIC50: 166nMAssay Description:Antagonist activity at human EP4R assessed as inhibition of agonist-induced cAMP production by fluorescent cAMP tracer cAMP-d2 based FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer

Curated by ChEMBL
LigandPNGBDBM261844(2-(9-Ethyl-9H-carbazol-3-y1)-1-methyl-1 H-benzimid...)
Affinity DataIC50: 195nMT: 2°CAssay Description:4 μl of a cAMP-d2/cell suspension (625000 cells/ml) were added to a test plate containing the substance solutions already initially introduced (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/31/2018
Entry Details
US Patent