BDBM26221 (3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(morpholin-4-yl)butanamido]-5-oxo-decahydropyrrolo[1,2-a]azocine-3-carboxamide::bicyclic Smac peptide mimetic, 23

SMILES CC[C@H](N1CCOCC1)C(=O)N[C@H]1CCCC[C@H]2CC[C@H](N2C1=O)C(=O)NC(c1ccccc1)c1ccccc1

InChI Key InChIKey=OYMUMWGTIVZDEF-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26221   

TargetE3 ubiquitin-protein ligase XIAP [241-356](Human)
University of Michigan

LigandPNGBDBM26221((3S,6S,10aS)-N-(diphenylmethyl)-6-[(2S)-2-(morphol...)
Affinity DataKi:  3.29E+4nM ΔG°:  -6.05kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization was measured on an Ultra plate reader at excitation and emission wavelengths of 485 and 530 nm, respectively. The equilibri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/3/2009
Entry Details Article
PubMed