BDBM26309 CHEMBL459888::N-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)phenyl]-3-(trifluoromethyl)benzamide::thieno[3,2-d]pyrimidine analogue, 1

SMILES FC(F)(F)c1cccc(c1)C(=O)Nc1ccc(CCNc2ncnc3ccsc23)cc1

InChI Key InChIKey=LSCKUUOMMSYITN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26309   

TargetAurora kinase A(Mouse)
Sunesis Pharmaceuticals

LigandPNGBDBM26309(N-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50: 3.20E+3nMpH: 7.2 T: 2°CAssay Description:Compounds were diluted into assay buffer containing Aurora kinase and FAM-PKAtide. The kinase reaction was initiated by adding ATP in assay buffer. T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2009
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM26309(N-[4-(2-{thieno[3,2-d]pyrimidin-4-ylamino}ethyl)ph...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of aurora A kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed