BDBM26370 3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3-(trifluoromethyl)phenyl]urea::Aminoquinazoline amide urea, 36

SMILES Cc1ccc(NC(=O)Nc2cccc(c2)C(F)(F)F)cc1-c1ccc2nc(N)ncc2c1

InChI Key InChIKey=BIPPSOZOQMDQPZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26370   

TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM26370(3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM26370(3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3...)
Affinity DataIC50: 93nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26370(3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3...)
Affinity DataIC50: 169nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26370(3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3...)
Affinity DataIC50: 28nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26370(3-[3-(2-aminoquinazolin-6-yl)-4-methylphenyl]-1-[3...)
Affinity DataIC50: 3.04E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed