BDBM26388 2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)phenyl]amino}pyrimidin-5-yl)-1-N-[3-(trifluoromethyl)benzene]benzene-1,3-dicarboxamide::Aminopyrimidine amide, 29

SMILES CN1CCN(CC1)c1ccc(Nc2ncc(NC(=O)c3c(C)ccc(NC(=O)c4cccc(c4)C(F)(F)F)c3C)cn2)cc1

InChI Key InChIKey=AERKVHQMODYBFE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26388   

TargetTyrosine-protein kinase Lck(Human)
Amgen

LigandPNGBDBM26388(2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Amgen

LigandPNGBDBM26388(2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26388(2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 2.54E+3nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26388(2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 103nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed
LigandPNGBDBM26388(2,4-dimethyl-3-N-(2-{[4-(4-methylpiperazin-1-yl)ph...)
Affinity DataIC50: 2.50E+4nMAssay Description:The assay involves the phosphorylation of a biotinylated substrate and the detection of this phosphorylation after the addition of a streptavidin-all...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2009
Entry Details Article
PubMed