BDBM264714 (R)-1-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-2,3-::US9718780, 1

SMILES OC[C@@H](O)C(=O)c1cccc(n1)-c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=DXYMJRXFBLAWFS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 264714   

LigandPNGBDBM264714((R)-1-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataIC50: 133nMAssay Description:In vitro assays were performed in a recombinant cell line expressing cDNA encoding the alpha subunit (Nav1.7, SCN9a, PN1, NE) of human Nav1.7 (Access...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/16/2018
Entry Details
Go to US Patent

LigandPNGBDBM264714((R)-1-(6-(4-(4-fluorophenoxy)phenyl)pyridin-2-yl)-...)
Affinity DataIC50: 133nMAssay Description:Inhibition of human Nav1.7 expressed in HEK293 cells by FLIPR methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed