BDBM26583 4-{[(2-carboxy-2-methylethyl)sulfanyl]methyl}-5-methylfuran-2-carboxylic acid::H1-A1NI2, 8

SMILES CC(CSCc1cc(oc1C)C(O)=O)C(O)=O

InChI Key InChIKey=ZKIDELUROHTLAV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26583   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandPNGBDBM26583(4-{[(2-carboxy-2-methylethyl)sulfanyl]methyl}-5-me...)
Affinity DataIC50: 2.20E+4nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed