BDBM26593 3-(5-{[(5E)-3-(carboxymethyl)-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)benzoic acid::A1NI2-A3NI1,18

SMILES OC(=O)CN1C(=S)S\C(=C\c2ccc(o2)-c2cccc(c2)C(O)=O)C1=O

InChI Key InChIKey=YYSBLZVXTCMYQK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26593   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
University of Southern California

LigandPNGBDBM26593(3-(5-{[(5E)-3-(carboxymethyl)-4-oxo-2-sulfanyliden...)
Affinity DataIC50: 6.00E+3nMpH: 7.5 T: 2°CAssay Description:To determine the extent of abasic residue cleavage by APE1, recombinant APE1 was preincubated with the potential inhibitors in reaction buffer. Then,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2009
Entry Details Article
PubMed