BDBM26680 2-oxo-4-(thiophen-2-yl)-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile::pyridone-based compound, 8

SMILES FC(F)(F)c1cc(-c2cccs2)c(C#N)c(=O)[nH]1

InChI Key InChIKey=WEYDUSXTIDLIMM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 26680   

TargetSerine/threonine-protein kinase pim-1(Human)
Valeant Pharmaceuticals Research and Development

LigandPNGBDBM26680(2-oxo-4-(thiophen-2-yl)-6-(trifluoromethyl)-1,2-di...)
Affinity DataIC50: 3.54E+3nMpH: 7.5 T: 2°CAssay Description:PIM-1 kinase activity was evaluated using calf thymus histones as the substrate in a 96-well filter plate format. After incubation, the plate was was...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2009
Entry Details Article
PubMed