BDBM267208 (1-{3-[1-(7-Chloro- quinoxalin-2-yl)-azetidin-3- yl]-pyrazin-2-yl}-piperidin- 4-yl)-methanol::US9718803, 28.17

SMILES OCC1CCN(CC1)c1nccnc1C1CN(C1)c1ccc2ccc(Cl)cc2n1

InChI Key InChIKey=XIDULMZNZIFLGC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 267208   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

US Patent

LigandBDBM267208((1-{3-[1-(7-Chloro- quinoxalin-2-yl)-azetidin-3- y...)Copy SMILESCopy InChI

Affinity DataIC50: 0.5nMT: 2°CAssay Description:An IMAP TR-FRET assay was used to analyze the enzyme activity (Molecular Devices Corp., Sunnyvale Calif.). 5 L of serial diluted PDE10A (BPS Bioscien...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/27/2018
Entry Details
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