BDBM269511 US10058550, Example 543.0::yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propanesulfonamide

SMILES CO[C@H]([C@@H](C)S(=O)(=O)Nc1nnc(-c2cncc(C)c2)n1-c1c(OC)cccc1OC)c1ncc(C)cn1

InChI Key InChIKey=AUANDMQSYRXQEK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 269511   

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM269511(yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propane...)
Affinity DataEC50:  62nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent

TargetApelin receptor(Human)
Amgen

US Patent
LigandPNGBDBM269511(yl)-1-methoxy-1-(5-methyl-2-pyrimidinyl)-2-propane...)
Affinity DataEC50:  62nMpH: 7.5Assay Description:The human APJ receptor was cloned by polymerase chain reaction and the gene encoding the receptor was subcloned in pFLAG-CMV -3 expression vector (Si...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2018
Entry Details
US Patent