BDBM2696 3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1H-indol-3-yl)-2,5-dihydro-1H-pyrrole-2,5-dione::Bisindolylmaleimide deriv. 5a

SMILES Cn1cc(C2=C(C(=O)NC2=O)c2c3CCCn3c3ccccc23)c2ccccc12

InChI Key InChIKey=QJISCZMEOOQPLS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 2696   

TargetProtein kinase C beta type(Rat)
Roche Products

LigandPNGBDBM2696(3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1...)
Affinity DataIC50: 210nMpH: 7.5 T: 2°CAssay Description:The activity of PKC, activated by phosphatidylerine and Ca2+, is measured by its ability to transfer phosphate from [gamma-32P]ATP to lysine-rich his...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed
LigandPNGBDBM2696(3-{1H,2H,3H-benzo[b]pyrrolizin-9-yl}-4-(1-methyl-1...)
Affinity DataIC50: 6.80E+4nMpH: 8.5 T: 2°CAssay Description:The activity of PKA, activated by cAMP, is measured by its ability to transfer phosphate from [gamma-32P]ATP to histone.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2004
Entry Details Article
PubMed