BDBM273210 5-Amino-3-[(2R,3S,5S)-5-(hydroxymethyl)-3-[(S)-hydroxy(2-pyridyl)methyl]tetrahydrofuran-2-yl]-6H-thiazolo[4,5-d]pyrimidine-2,7-dione::US10065973, Example 7

SMILES [H][C@@]1(CO)C[C@@]([H])(C(O)c2ccccn2)[C@@H](O1)n1c2nc(N)[nH]c(=O)c2sc1=O

InChI Key InChIKey=XNHCUOJBYGQLJH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 273210   

TargetToll-like receptor 7(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM273210(5-Amino-3-[(2R,3S,5S)-5-(hydroxymethyl)-3-[(S)-hyd...)
Affinity DataEC50:  2.25E+5nMAssay Description:HEK293-Blue-hTLR7 cells were incubated at a density of 250,000-450,000 cells/mL in a volume of 180 μL in a 96-well plate in Dulbecco's Modif...More data for this Ligand-Target Pair
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Date in BDB:
12/11/2018
Entry Details
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