BDBM27466 2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)benzamide::Amino-substituted diarylbenzamide, 8g

SMILES NC(=O)c1cc(cc(c1N)-c1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1

InChI Key InChIKey=JQFFORXNDDEBAU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27466   

LigandPNGBDBM27466(2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)be...)
Affinity DataIC50: 200nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
LigandPNGBDBM27466(2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)be...)
Affinity DataIC50: 501nMpH: 7.4 T: 2°CAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
LigandPNGBDBM27466(2-amino-5-(4-fluorophenyl)-3-(4-sulfamoylphenyl)be...)
Affinity DataIC50: 1.58E+4nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed