BDBM27489 2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-phenylbenzamide::Amino-substituted diarylbenzamide, 8v

SMILES NCCNS(=O)(=O)c1ccc(cc1)-c1cc(cc(C(N)=O)c1N)-c1ccccc1

InChI Key InChIKey=BWZCCEYPZOYICS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 27489   

TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)
Affinity DataIC50: 158nMAssay Description:Inhibition of human IKKbeta using GST-IkappaBalpha as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)
Affinity DataIC50: 158nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)
Affinity DataIC50: 631nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed
LigandPNGBDBM27489(2-amino-3-{4-[(2-aminoethyl)sulfamoyl]phenyl}-5-ph...)
Affinity DataIC50: 1.58E+4nMAssay Description:IKK kinase activity was assessed using a time-resolved fluorescence resonance energy transfer (TR-FRET) assay. The reaction was initiated by the addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMed