BDBM27586 (E)-alkene compound, 9::2-(4-{3-chloro-4-[(4E)-5-(2-chloro-4-methylphenyl)hex-4-enamido]phenyl}phenoxy)acetic acid

SMILES C\C(=C/CCC(=O)Nc1ccc(cc1Cl)-c1ccc(OCC(O)=O)cc1)c1ccc(C)cc1Cl

InChI Key InChIKey=JGEXIGKIMXNLEM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27586   

TargetGag-Pol polyprotein [588-1027](HIV-1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27586(2-(4-{3-chloro-4-[(4E)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 272nMpH: 7.4 T: 2°CAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Boehringer Ingelheim (Canada)

LigandPNGBDBM27586(2-(4-{3-chloro-4-[(4E)-5-(2-chloro-4-methylphenyl)...)
Affinity DataIC50: 3.27E+3nMAssay Description:IC50 values for wild-type and mutant RTs were obtained from a scintillation proximity assay using poly rC/biotin-dG15 and 3H-dGTP. Each value represe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed