BDBM27654 1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-yl)-N-[(2-fluorophenyl)methyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide::pyrazole scaffold, 10b

SMILES C[C@H](N)C(=O)NCc1ccc(s1)-n1nc(cc1C(=O)NCc1ccccc1F)C(F)(F)F

InChI Key InChIKey=HRRYWPRDAOKUSC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27654   

LigandPNGBDBM27654(1-(5-{[(2S)-2-aminopropanamido]methyl}thiophen-2-y...)
Affinity DataIC50: 2.31E+3nMpH: 9.0 T: 2°CAssay Description:Histone H3 is used as the substrate for CARM-1 enzyme, and the methylation is monitored using tritiated S-Adenosyl-Methionine (SAM) as a methyl donor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2009
Entry Details Article
PubMed