BDBM277090 4-(2,4-difluorophenyl)-7- {[1-(1-methylethyl)-1H- pyrazol-5-yl]methyl}- 5,6,7,8-tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-9

SMILES CC(C)n1nccc1CN1CCc2c(C1)nc(cc2-c1ccc(F)cc1F)C(N)=O

InChI Key InChIKey=KMECIHLYHLMXNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277090   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277090(US10072003, Example 1-9 | 4-(2,4-difluorophenyl)-7...)
Affinity DataIC50: 8.20E+3nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
US Patent