BDBM277099 4-(4-chloro-2- fluorophenyl)-7-[(1- methyl-1H-imidazol-5- yl)methyl]-5,6,7,8- tetrahydro-1,7- naphthyridine-2- carboxamide::US10072003, Example 1-16

SMILES Cn1cncc1CN1CCc2c(C1)nc(cc2-c1ccc(Cl)cc1F)C(N)=O

InChI Key InChIKey=FAYPOOFPPLKTDF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277099   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277099(US10072003, Example 1-16 | 4-(4-chloro-2- fluoroph...)
Affinity DataIC50: 1.41E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
US Patent