BDBM277106 US10072003, Example 1-23A::US10072003, Example 1-23B

SMILES CC1(C)CC(CN2CCc3c(cc(nc3C2(C)C)C(N)=O)-c2ccc(F)cc2F)CCO1

InChI Key InChIKey=ZTRSFIZEUDQNGZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 277106   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277106(US10072003, Example 1-23B | US10072003, Example 1-...)
Affinity DataIC50: 1.47E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277106(US10072003, Example 1-23B | US10072003, Example 1-...)
Affinity DataIC50: 2.85E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
Go to US Patent