BDBM277174 4-(4-chloro-2-fluorophenyl)-7-[(3-methyl- 1,2,4-oxadiazol-5-yl)methyl]-5,6,7,8- tetrahydro-1,7-naphthyridine-2-carboxamide::US10072003, Example 9-5

SMILES Cc1noc(CN2CCc3c(C2)nc(cc3-c2ccc(Cl)cc2F)C(N)=O)n1

InChI Key InChIKey=DFICSNRKVWAORW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277174   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277174(US10072003, Example 9-5 | 4-(4-chloro-2-fluorophen...)
Affinity DataIC50: 1.27E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
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