BDBM277179 4-(4-chloro-2-fluorophenyl)-7-(pyridin-3- ylmethyl)-5,6,7,8-tetrahydro-1,7- naphthyridine-2-carboxamide::US10072003, Example 10-3

SMILES NC(=O)c1cc(c2CCN(Cc3cccnc3)Cc2n1)-c1ccc(Cl)cc1F

InChI Key InChIKey=BEPKCUPKYPRHOA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277179   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277179(US10072003, Example 10-3 | 4-(4-chloro-2-fluorophe...)
Affinity DataIC50: 1.20E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
US Patent