BDBM277186 7-{[2-(trifluoromethyl)pyrimidin-4- yl]methyl}-4-(2,4,6-trifluorophenyl)- 5,6,7,8-tetrahydro-1,7-naphthyridine-2- carboxamide::US10072003, Example 11-6

SMILES NC(=O)c1cc(c2CCN(Cc3ccnc(n3)C(F)(F)F)Cc2n1)-c1c(F)cc(F)cc1F

InChI Key InChIKey=VIPYICZAVOKSOT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277186   

TargetMetabotropic glutamate receptor 2(Human)
TBA

US Patent
LigandPNGBDBM277186(US10072003, Example 11-6 | 7-{[2-(trifluoromethyl)...)
Affinity DataIC50: 1.32E+4nMAssay Description:The utility of the compounds of the invention as antagonists of metabotropic glutamate receptor activity, in particular mGluR2 activity, may be demon...More data for this Ligand-Target Pair
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Date in BDB:
12/21/2018
Entry Details
US Patent