BDBM27722 3-[4-(trifluoromethyl)phenyl]quinoxaline-5-carboxamide::CHEMBL521428::quinoxaline analogue, 3d

SMILES NC(=O)c1cccc2ncc(nc12)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=TVFZZQMNVBEMRP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 27722   

TargetPoly [ADP-ribose] polymerase 2(Mouse)
Fujisawa Pharmaceutical

LigandPNGBDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 11nMT: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 118nMpH: 8.0 T: 2°CAssay Description:To assess the inhibitory activity of novel inhibitors, the PARP enzyme assay was carried out in reaction mixture consisting of activated salmon teste...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2009
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Fujisawa Pharmaceutical

LigandPNGBDBM27722(CHEMBL521428 | 3-[4-(trifluoromethyl)phenyl]quinox...)
Affinity DataIC50: 118nMAssay Description:Inhibition of human recombinant PARP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed