BDBM277317 1-(1'-phenethyl-1H-spiro[isoquinoline-3,4'-piperidine]-2(4H)-yl)-::US10072008, Example 5

SMILES CC(=O)N1Cc2ccccc2CC11CCN(CCc2ccccc2)CC1

InChI Key InChIKey=SHHPKWDTHMVMDE-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277317   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277317(US10072008, Example 5 | 1-(1'-phenethyl-1H-spiro[i...)
Affinity DataKi: <500nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent