BDBM277318 1'-benzyl-2-methyl-2,4-dihydro-1H-spiro[isoquinoline-3,4'-piperidine]::US10072008, Example 6

SMILES CN1Cc2ccccc2CC11CCN(Cc2ccccc2)CC1

InChI Key InChIKey=BZKWUTHIHXFWBB-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 277318   

TargetSigma non-opioid intracellular receptor 1(Human)
Esteve Pharmaceuticals

US Patent
LigandPNGBDBM277318(US10072008, Example 6 | 1'-benzyl-2-methyl-2,4-dih...)
Affinity DataKi: <100nMpH: 8.0Assay Description:To investigate binding properties of test compounds to human σ1 receptor, transfected HEK-293 membranes and [3H](+)-pentazocine (Perkin Elmer, N...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/21/2018
Entry Details
US Patent