BDBM27752 N-{3-[(3-chloro-4-fluorophenyl)methyl]-9-hydroxy-7-methyl-8-oxo-6H,7H,8H-pyrrolo[3,4-g]quinolin-5-yl}-N-methylmethanesulfonamide::tricyclic pyrroloquinoline, 21

SMILES CN(c1c2CN(C)C(=O)c2c(O)c2ncc(Cc3ccc(F)c(Cl)c3)cc12)S(C)(=O)=O

InChI Key InChIKey=OXVUJFNJJBBQAM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27752   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27752(N-{3-[(3-chloro-4-fluorophenyl)methyl]-9-hydroxy-7...)
Affinity DataIC50: 265nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
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Date in BDB:
3/23/2009
Entry Details Article
PubMed