BDBM27985 2-{[(3-chlorophenyl)methyl]amino}-N-(2-phenoxyethyl)-4-(3,4,5-trimethoxyphenyl)pyrimidine-5-carboxamide::trisubstituted pyrimidine analogue, 6f

SMILES COc1cc(cc(OC)c1OC)-c1nc(NCc2cccc(Cl)c2)ncc1C(=O)NCCOc1ccccc1

InChI Key InChIKey=PPGJXQJJPCTCCH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27985   

TargetExtracellular calcium-sensing receptor(Human)
Bristol-Myers Squibb

LigandPNGBDBM27985(2-{[(3-chlorophenyl)methyl]amino}-N-(2-phenoxyethy...)
Affinity DataIC50: 70nMpH: 7.5 T: 2°CAssay Description:Antagonist activity of test compounds was measured in HEK293 cells stably expressing the human recombinant CaR (HEK-CaR) by determining the ability o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/5/2009
Entry Details Article
PubMed