BDBM280397 US10030012, Example 27::ethyl 4-[4-(5- cyano-1H- pyrazol-1- yl)piperidin-1- yl]azepane-1- carboxylate

SMILES CCOC(=O)N1CCCC(CC1)N1CCC(CC1)n1nccc1C#N

InChI Key InChIKey=YCEQSNMUIHRPCF-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280397   

TargetMuscarinic acetylcholine receptor M4(Human)
Heptares Therapeutics

US Patent
LigandPNGBDBM280397(ethyl 4-[4-(5- cyano-1H- pyrazol-1- yl)piperidin-1...)
Affinity DataEC50:  320nMAssay Description:The functional activity of compounds at the M4 and M2 receptors was determined by measuring changes in the level of intracellular calcium ions caused...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2018
Entry Details
US Patent