BDBM280991 (12S,15S,18S)-15-(3-Amino-propyl)-18-biphenyl-4-ylmethyl-12-(1H-indol-3-ylmethyl)-19-methyl-2-thia-10,13,16,19-tetraaza-tricyclo[19.4.0.0*3,8*]pentacosa-1(25),3,5,7,21,23-hexaene-11,14,17-trione::US10030047, Example 117

SMILES CN1Cc2ccccc2Sc2ccccc2CNC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@H](CCCN)NC(=O)[C@@H]1Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HASXMLVWLZDEJT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 280991   

TargetAdhesin Ata autotransporter(Acinetobacter baumannii (strain ATCC 17978 / CIP 5...)
Hoffmann-La Roche

US Patent
LigandPNGBDBM280991((12S,15S,18S)-15-(3-Amino-propyl)-18-biphenyl-4-yl...)
Affinity DataIC50: 8.10E+3nMAssay Description:The in vitro antimicrobial activity of the compounds was alternatively determined according to the following procedure:The assay used a 10-points Iso...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details
US Patent