BDBM28111 3-cyanoquinoline, 36::4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-2-yl)sulfanyl]phenyl}amino)-6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinoline-3-carbonitrile

SMILES CCn1c(C)c(C)nc1Sc1ccc(Nc2c(cnc3cc(OCCCN4CCOCC4)c(OC)cc23)C#N)cc1Cl

InChI Key InChIKey=LUWFHHJOLCXYBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28111   

TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28111(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 15nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed