BDBM282570 (3R)-5-(3-chloro-5-fluoro-phenoxy)-3-hydroxy-1,1- dioxo-2,3-dihydrobenzothiophene-4-carbonitrile::US9884843, Compound 2

SMILES O[C@H]1CS(=O)(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(C#N)c12

InChI Key InChIKey=IHQLDRVSYYRWIM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 282570   

TargetVascular endothelial growth factor A(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM282570(US9884843, Compound 2 | (3R)-5-(3-chloro-5-fluoro-...)
Affinity DataIC50: 47nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent