BDBM282578 US9884843, Compound 7

SMILES OC1CS(=O)(=O)c2ccc(Oc3cc(F)cc(Cl)c3)c(C#N)c12

InChI Key InChIKey=IHQLDRVSYYRWIM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282578   

TargetVascular endothelial growth factor A(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM282578(US9884843, Compound 7)
Affinity DataIC50: 61nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetVascular endothelial growth factor A(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM282578(US9884843, Compound 7)
Affinity DataEC50:  330nMAssay Description:About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent