BDBM282713 (R)-4-Bromo-5-(3-chloro-5-fluoro-phenoxy)-2,2- difluoro-1,1-dioxo-3H-benzothiophen-3-ol::US9884843, Compound 57

SMILES O[C@@H]1c2c(ccc(Oc3cc(F)cc(Cl)c3)c2Br)S(=O)(=O)C1(F)F

InChI Key InChIKey=QDJHBOPWDGYCGJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 282713   

TargetVascular endothelial growth factor A(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM282713(US9884843, Compound 57 | (R)-4-Bromo-5-(3-chloro-5...)
Affinity DataIC50: 5nMpH: 7.5Assay Description:The total assay volume was about 100 μL in the following configuration: 2-μL compound in DMSO, 88 μL buffer with protein and probe and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent

TargetVascular endothelial growth factor A(Human)
Peloton Therapeutics

US Patent
LigandPNGBDBM282713(US9884843, Compound 57 | (R)-4-Bromo-5-(3-chloro-5...)
Affinity DataEC50:  45nMAssay Description:About 7500 of 786-O cells in 180 μL of growth medium were seeded into each well of a 96 well plate with white clear bottom on the first day (07-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2019
Entry Details
US Patent