BDBM28439 (2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-9-yl]-5-{[(3-aminopropyl)(methyl)amino]methyl}oxolane-3,4-diol::AdoMet substrate analogue, 18a

SMILES CNc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CN(C)CCCN)[C@@H](O)[C@H]1O

InChI Key InChIKey=FGKVLNQCVWKBGW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28439   

TargetS-adenosylmethionine decarboxylase proenzyme(Human)
Cornell University

LigandPNGBDBM28439((2R,3R,4S,5R)-2-[6-amino-8-(methylamino)-9H-purin-...)
Affinity DataIC50: 4.40E+5nMpH: 6.8 T: 2°CAssay Description:The C-terminal his-tagged AdoMetDC was assayed by measuring the release of 14CO2 from S-adenosyl-L-[carboxy-14C]methionine (Amersham Pharmacia Biotec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/21/2009
Entry Details Article
PubMed