BDBM28461 (2S)-2-({12-methanesulfonamido-8-oxatricyclo[7.4.0.0^{2,7}]trideca-1(9),2(7),3,5,10,12-hexaene-5-}sulfonamido)-3-methylbutanoic acid::dibenzofuran (DBF) scaffold, (S)-7

SMILES CC(C)[C@H](NS(=O)(=O)c1ccc2c(c1)oc1ccc(NS(C)(=O)=O)cc21)C(O)=O

InChI Key InChIKey=PASQOFLVNKNUQM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28461   

TargetMacrophage metalloelastase(Human)
Wyeth Research

LigandPNGBDBM28461((2S)-2-({12-methanesulfonamido-8-oxatricyclo[7.4.0...)
Affinity DataIC50: 10.3nMpH: 7.5 T: 2°CAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Wyeth Research

LigandPNGBDBM28461((2S)-2-({12-methanesulfonamido-8-oxatricyclo[7.4.0...)
Affinity DataIC50: 93nMAssay Description:The assays for human MMP activity were performed by incubating fluorogenic peptide substrate with recombinant human MMP catalytic domain along with v...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2009
Entry Details Article
PubMed