BDBM284893 4-acetyl-1-(5-(4-amino-5-(1- (tetrahydro-2H-pyran-4-yl)-1H-pyrazol- 5-yl)pyrrolo[2,1-f][1,2,4]triazin-7- yl)pyridin-3-yl)-3,3-dimethylpiperazin- 2-one::US10023576, Example 84

SMILES CC(=O)N1CCN(C(=O)C1(C)C)c1cncc(c1)-c1cc(-c2ccnn2C2CCOCC2)c2c(N)ncnn12

InChI Key InChIKey=UAEUEOBVYYHUDF-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284893   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Bristol-Myers Squibb

US Patent

LigandBDBM284893(US10023576, Example 84 | 4-acetyl-1-(5-(4-amino-5-...)Copy SMILESCopy InChI

Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:The ADP-Glo format PI3K assays were performed in Proxiplate 384-well plates (Perkin Elmer #6008280). The final assay volume was 2 μl prepared fr...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
1/11/2019
Entry Details
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