BDBM28548 4-methanesulfonyl-N,12-dimethyl-5-thia-3,7,10,12-tetraazatricyclo[7.3.0.0^{2,6}]dodeca-1(9),2(6),3,7,10-pentaen-8-amine::thiazole-based tricyclic inhibitor, 20

SMILES CNc1nc2sc(nc2c2n(C)cnc12)S(C)(=O)=O

InChI Key InChIKey=CUFUQFXOHLGNNW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 28548   

LigandPNGBDBM28548(4-methanesulfonyl-N,12-dimethyl-5-thia-3,7,10,12-t...)
Affinity DataIC50: 81nMpH: 7.5 T: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed
LigandPNGBDBM28548(4-methanesulfonyl-N,12-dimethyl-5-thia-3,7,10,12-t...)
Affinity DataIC50: 7.60E+3nMT: 2°CAssay Description:Assays measuring the enzyme catalyzed phosphorylation of GST-I-kappa-B-alpha were performed by adding enzyme at room temperature to substrate solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/2/2009
Entry Details Article
PubMed