BDBM285503 4-[4-Cyano-2-({[(2′R,4S)-7-fluoro-6-(isopropylcarbamoyl)-2,3-dihydrospiro[chromene-4, 1′-cyclopropan]-2′-yl]carbonyl}amino)phenyl]butanoic acid::US10077247, Example 20-5

SMILES CC(C)NC(=O)c1cc2c(OCC[C@]22C[C@H]2C(=O)Nc2cc(ccc2CCCC(O)=O)C#N)cc1F

InChI Key InChIKey=FVALLBPEEPBOMY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285503   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM285503(US10077247, Example 20-5 | 4-[4-Cyano-2-({[(2̸...)
Affinity DataIC50: 9.5nMT: 2°CAssay Description:EP4 Antagonistic Activity Measurement Experiment Using Prostanoid Receptor Subtype Expressing CellsCHO cells expressing rat EP4 receptor subtypes wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2019
Entry Details
US Patent